Looking for Healthy Joint Supplements ? Try Cissus Quadrangularis

By | October 29, 2015

Cissus quadrangularisIf you are serious about working out and have been doing so for some time I am sure you have experienced joint pain. If you are holding back in the gym from joint pain then your output will not be as great as it can be nor your results. I came across Cissus quadragularis a while back and let me say I am glad I did.

Cissus quadrangularis is one of the best natural joint pain relief supplements I have tried. Best yet, it is all natural. Cissus is a succulent vine that has been used for medicinal purposes by native healers throughout Africa and Asia since ancient times. Usually the stem is ground into powder and ingested via pills. However it can also be ground and mixed into a paste and applied to the site of injury. It contains vitamins as well as steroids and has been used for a number of medical problems including obesity, diabetes, metabolic syndrome, high cholesterol, and skeletal strength (bone and joint) which I will be talking about.

My Experience

From years of lifting heavy weights I developed a pain in my right elbow which would be noticeably stimulated upon performing exercises where my arm would extend, such as any pressing movement. Usually I would wear an elbow sleeve when working out and/or put some ice on it after. It wasn’t an emergency or anything, but I didn’t want to have to worry about the pain all time. So I began researching. I saw that Cissus was an all natural product with great reviews so decided to give it a try.

I was pleasantly surprised by the result. It did not cure the problem but it did suppress the pain. Not only did it help with the existing pain, but I did not experience any other new joint pains while using which is unusual considering the length of time I used it and the fact that I love to lift heavy.

I went through two bottles of Cissus (I believe they were both a 5 week supply) with a couple week break in between the first and the second. After the first bottle was up I wasn’t convinced that it had certainly been the variable that lead to my decreased pain. I thought it could just have been a coincidence and that my pain just “decided” to go away at the same time I began supplementing. After several weeks without Cissus I began to develop a very minor shoulder pain along with my existing elbow pain. It was nothing serious but I wanted to test out the product once more. Again, the same result! The pain in my shoulder had completely disappeared while the elbow pain was suppressed once more.

With two separate occasions of Cissus quadrangularis working as it did I am convinced it was not just a coincidence. Upon further research which is included below, I am wondering if my elbow problem could recover completely with longer supplementation (more than 5 weeks). It could be that I am continually beating my elbow joint down and down again without adequate recovery time. Cissus might be just what I need to give my joint a little boost in speed of healing.

Modern Studies

Phytochemical research studies have found that Cissus quadrangularis contains vitamin C, calcium, and anabolic Cissus Quadrangularis Studysteroidal substances among others. Studies conducted suggest that an unidentified phytogenic isolated steroid is the most likely the variable responsible for the majority of Cissus’ healing and strengthening abilities. This anabolic steroid is thought to work on the bone’s estrogen receptors. Once the plant enters the body (ingestion, topical, etc) it boosts the metabolism which leads to the osteoblasts involved in the healing process using more calcium, sulpher, and strontium.


Udupa and Prasad, an Indian team of medical researchers, investigated the healing claims and conducted studies on Cissus quadrangularis in both animal and human studies. The first study involved Cissus paste being applied to the site of fractured bones. The results were quite conclusive; it works! The healing time of the fractured bones in the human test subjects was reduced by approx. two weeks and for the animal test subjects (dogs) it was reduced by approx. one third (1).

A second study conducted on rats further proved Cissus’ amazing healing abilities. This time plant extract was dissolved in ethylene glycol and injected into the test’s muscles near the site of bone fracture. Here it reduced the healing time once again by one fourth (1).

Bone Strength

Another group of studies were performed by administering a petroleum ether extract of Cissus to rat test subjects.

In the first study the strength of the femur bone was tested before and after the supplementation of Cissus quadrangularis. Rats were given 500mg of Cissus extract per kilogram of body weight for 90 days. After this period the force required to break the femur was tested (animal cruelty). I could not find the additional amount of force that was required but it was said to be a significant amount. Also the ortical and trabecular bones showed and increase in overall diameter.

Moving on to another study with rat test subjects, they were given the same dosage of 500mg of extract per kilogram of body weight for 30 days. The findings were that the tartrate-resist acid phosphatase and alkaline phosphatase activities’ serum levels had grown and that the trabecular and ortical bones had grown in thickness.

What does this all mean?

It shows that Cissus quadrangularis has anti-osteoporotic qualities, making bones stronger and healthier, and can be used to help prevent or reverse the effects of osteoporosis (osteoporosis is a bone disease that causes bones to become fragile and more likely to break).

Besides being very beneficial for skeletal strength and health Cissus has anti-inflammatory, antihemorrhoidal, antiulcer, parasympathomimetic, antioxidant, antiosteoporotic, and analgesic properties which you can look more into if interested.



1) Mishra, Garima, Saurabh Srivastava, and B.P. Nagori. “Pharmacological and Therapeutic Activity of Cissus Quadrangularis: An Overview.”International Journal of PharmTech Research 2.2 (2010): 1298-310. Web. 27 Oct. 2015.

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